Saturday, December 5, 2015

HYPERTHYROIDISM

Introduction

Thyrotoxicosis is the clinical syndrome that results from elevated levels of circulating thyroid hormones
Hyperthyroidism (thyroid overactivity, thyrotoxicosis) is common, affecting perhaps 2–5% of all females at some time and with a sex ratio of 5:1, most often between the ages of 20 and 40 years

Pathogenesis

Thyroid hormone increases oxygen consumption by tissues, raising heat production and energy metabolism. It interacts with the sympathetic nervous system in a way that seems to increase tissue sensitivity to catecholamines and adrenergic stimuli (Tachycardia and extremity tremor are the examples of catecholamines hypersensitivity)